MDM2 Regulation of HIF Signaling Causes Microvascular Dysfunction in Hypertrophic Cardiomyopathy

BACKGROUND: Microvasculature dysfunction is a common finding in pathologic remodeling of the heart and is thought to play an important role in the pathogenesis of hypertrophic cardiomyopathy (HCM), a disease caused by sarcomere gene mutations. We hypothesized that microvascular dysfunction in HCM wa...

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Detalles Bibliográficos
Autores principales: Shridhar, Puneeth, Glennon, Michael S., Pal, Soumojit, Waldron, Christina J., Chetkof, Ethan J., Basak, Payel, Clavere, Nicolas G., Banerjee, Dipanjan, Gingras, Sebastien, Becker, Jason R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691664/
https://www.ncbi.nlm.nih.gov/pubmed/37886847
http://dx.doi.org/10.1161/CIRCULATIONAHA.123.064332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691664/
https://www.ncbi.nlm.nih.gov/pubmed/37886847
http://dx.doi.org/10.1161/CIRCULATIONAHA.123.064332

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