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MDM2 Regulation of HIF Signaling Causes Microvascular Dysfunction in Hypertrophic Cardiomyopathy

BACKGROUND: Microvasculature dysfunction is a common finding in pathologic remodeling of the heart and is thought to play an important role in the pathogenesis of hypertrophic cardiomyopathy (HCM), a disease caused by sarcomere gene mutations. We hypothesized that microvascular dysfunction in HCM wa...

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Detalles Bibliográficos
Autores principales:	Shridhar, Puneeth, Glennon, Michael S., Pal, Soumojit, Waldron, Christina J., Chetkof, Ethan J., Basak, Payel, Clavere, Nicolas G., Banerjee, Dipanjan, Gingras, Sebastien, Becker, Jason R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	Original Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691664/ https://www.ncbi.nlm.nih.gov/pubmed/37886847 http://dx.doi.org/10.1161/CIRCULATIONAHA.123.064332

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