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CAR-modified Cellular Therapies in Chronic Lymphocytic Leukemia: Is the Uphill Road Getting Less Steep?

The clinical development of chimeric antigen receptor (CAR) T-cell therapy has been more challenging for chronic lymphocytic leukemia (CLL) compared to other settings. One of the main reasons is the CLL-associated state of immune dysfunction that specifically involves patient-derived T cells. Here,...

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Detalles Bibliográficos
Autores principales: Vitale, Candida, Griggio, Valentina, Perutelli, Francesca, Coscia, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691795/
https://www.ncbi.nlm.nih.gov/pubmed/38044959
http://dx.doi.org/10.1097/HS9.0000000000000988