The role of antidrug antibodies in ustekinumab therapy and the impact of methotrexate

OBJECTIVE: We investigated the impact of concomitant MTX on ustekinumab (UST) levels and antidrug antibody (ADA) formation in PsA and evaluated consequences in pharmacodynamics and pharmacokinetics. METHODS: We conducted a post-hoc analysis on 112 PsA serum samples of subjects treated with open-labe...

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Detalles Bibliográficos
Autores principales: Mojtahed Poor, Sorwe, Henke, Marina, Ulshöfer, Thomas, Köhm, Michaela, Behrens, Frank, Burkhardt, Harald, Schiffmann, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691926/
https://www.ncbi.nlm.nih.gov/pubmed/37079726
http://dx.doi.org/10.1093/rheumatology/kead177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691926/
https://www.ncbi.nlm.nih.gov/pubmed/37079726
http://dx.doi.org/10.1093/rheumatology/kead177

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