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Urolithin C alleviates pancreatic β-cell dysfunction in type 1 diabetes by activating Nrf2 signaling

AIMS: Type 1 diabetes (T1D) is an autoimmune disorder that destroys insulin-generating pancreatic β-cells. Preserving pancreatic β-cell function is important for treating T1D. Our study aims to explore the mechanism underlying urolithin C (UC)-mediated regulation of β-cell function. METHODS: Non-obe...

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Detalles Bibliográficos
Autores principales: Luo, Cheng, Hou, Can, Yang, Danyi, Tan, Tingting, Chao, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692094/
https://www.ncbi.nlm.nih.gov/pubmed/38040681
http://dx.doi.org/10.1038/s41387-023-00253-3