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The Notch1 signaling pathway directly modulates the human RANKL-induced osteoclastogenesis

Notch signaling is an evolutionary conserved pathway with a key role in tissue homeostasis, differentiation and proliferation. It was reported that Notch1 receptor negatively regulates mouse osteoclast development and formation by inhibiting the expression of macrophage colony-stimulating factor in...

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Detalles Bibliográficos
Autores principales: Padovano, Costanzo, Bianco, Salvatore Daniele, Sansico, Francesca, De Santis, Elisabetta, Tamiro, Francesco, Colucci, Mattia, Totti, Beatrice, Di Iasio, Serena, Bruno, Gaja, Panelli, Patrizio, Miscio, Giuseppe, Mazza, Tommaso, Giambra, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692129/
https://www.ncbi.nlm.nih.gov/pubmed/38040752
http://dx.doi.org/10.1038/s41598-023-48615-2