A simple method for developing lysine targeted covalent protein reagents

Peptide-based covalent probes can target shallow protein surfaces not typically addressable using small molecules, yet there is a need for versatile approaches to convert native peptide sequences into covalent binders that can target a broad range of residues. Here we report protein-based thio-metha...

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Detalles Bibliográficos
Autores principales: Gabizon, Ronen, Tivon, Barr, Reddi, Rambabu N., van den Oetelaar, Maxime C. M., Amartely, Hadar, Cossar, Peter J., Ottmann, Christian, London, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692228/
https://www.ncbi.nlm.nih.gov/pubmed/38040731
http://dx.doi.org/10.1038/s41467-023-42632-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692228/
https://www.ncbi.nlm.nih.gov/pubmed/38040731
http://dx.doi.org/10.1038/s41467-023-42632-5

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