Multi-domain and complex protein structure prediction using inter-domain interactions from deep learning

Accurately capturing domain-domain interactions is key to understanding protein function and designing structure-based drugs. Although AlphaFold2 has made a breakthrough on single domain, it should be noted that the structure modeling for multi-domain protein and complex remains a challenge. In this...

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Detalles Bibliográficos
Autores principales: Xia, Yuhao, Zhao, Kailong, Liu, Dong, Zhou, Xiaogen, Zhang, Guijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692239/
https://www.ncbi.nlm.nih.gov/pubmed/38040847
http://dx.doi.org/10.1038/s42003-023-05610-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692239/
https://www.ncbi.nlm.nih.gov/pubmed/38040847
http://dx.doi.org/10.1038/s42003-023-05610-7

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