Extracellular Fe(2+) and Fe(3+) modulate osteocytic viability, expression of SOST, RANKL and FGF23, and fluid flow-induced YAP1 nuclear translocation

Iron overload negatively affects bone mass and strength. However, the impact of iron excess on osteocytes—important bone cells for mechanotransduction and remodeling—is poorly understood. Herein, we examined the effects of iron exposure on osteocytes during their maturation process. We discovered th...

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Detalles Bibliográficos
Autores principales: Chankamngoen, Wasutorn, Krungchanuchat, Saowalak, Thongbunchoo, Jirawan, Sirinonthanawech, Naraporn, Teerapornpuntakit, Jarinthorn, Panupinthu, Nattapon, Charoenphandhu, Narattaphol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692318/
https://www.ncbi.nlm.nih.gov/pubmed/38040893
http://dx.doi.org/10.1038/s41598-023-48436-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692318/
https://www.ncbi.nlm.nih.gov/pubmed/38040893
http://dx.doi.org/10.1038/s41598-023-48436-3

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