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ADAR1 regulates vascular remodeling in hypoxic pulmonary hypertension through N1-methyladenosine modification of circCDK17

Pulmonary hypertension (PH) is an extremely malignant pulmonary vascular disease of unknown etiology. ADAR1 is an RNA editing enzyme that converts adenosine in RNA to inosine, thereby affecting RNA expression. However, the role of ADAR1 in PH development remains unclear. In the present study, we inv...

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Detalles Bibliográficos
Autores principales: Zhang, Junting, Li, Yiying, Zhang, Jianchao, Liu, Lu, Chen, Yuan, Yang, Xusheng, Liao, Xueyi, He, Muhua, Jia, Zihui, Fan, Jun, Bian, Jin-Song, Nie, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692360/
https://www.ncbi.nlm.nih.gov/pubmed/38045055
http://dx.doi.org/10.1016/j.apsb.2023.07.006