Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood–brain barrier and exhibits potent activity against glioblastoma

Glioblastoma (GBM) is the most common and aggressive malignant brain tumor in adults and is poorly controlled. Previous studies have shown that both macrophages and angiogenesis play significant roles in GBM progression, and co-targeting of CSF1R and VEGFR is likely to be an effective strategy for G...

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Detalles Bibliográficos
Autores principales: Liu, Yingqiang, Zhan, Zhengsheng, Kang, Zhuang, Li, Mengyuan, Lv, Yongcong, Li, Shenglan, Tong, Linjiang, Feng, Fang, Li, Yan, Zhang, Mengge, Xue, Yaping, Chen, Yi, Zhang, Tao, Song, Peiran, Su, Yi, Shen, Yanyan, Sun, Yiming, Yang, Xinying, Yao, Shanyan, Yang, Hanyu, Wang, Caixia, Geng, Meiyu, Li, Wenbin, Duan, Wenhu, Xie, Hua, Ding, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692396/
https://www.ncbi.nlm.nih.gov/pubmed/38045044
http://dx.doi.org/10.1016/j.apsb.2023.09.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692396/
https://www.ncbi.nlm.nih.gov/pubmed/38045044
http://dx.doi.org/10.1016/j.apsb.2023.09.009

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