Targeting autophagy and beyond: Deconvoluting the complexity of Beclin-1 from biological function to cancer therapy

Beclin-1 is the firstly-identified mammalian protein of the autophagy machinery, which functions as a molecular scaffold for the assembly of PI3KC3 (class III phosphatidylinositol 3 kinase) complex, thus controlling autophagy induction and other cellular trafficking events. Notably, there is mountin...

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Detalles Bibliográficos
Autores principales: Ye, Jing, Zhang, Jin, Zhu, Yanghui, Wang, Lian, Jiang, Xian, Liu, Bo, He, Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692397/
https://www.ncbi.nlm.nih.gov/pubmed/38045051
http://dx.doi.org/10.1016/j.apsb.2023.08.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692397/
https://www.ncbi.nlm.nih.gov/pubmed/38045051
http://dx.doi.org/10.1016/j.apsb.2023.08.008

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