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Targeting autophagy and beyond: Deconvoluting the complexity of Beclin-1 from biological function to cancer therapy
Beclin-1 is the firstly-identified mammalian protein of the autophagy machinery, which functions as a molecular scaffold for the assembly of PI3KC3 (class III phosphatidylinositol 3 kinase) complex, thus controlling autophagy induction and other cellular trafficking events. Notably, there is mountin...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692397/ https://www.ncbi.nlm.nih.gov/pubmed/38045051 http://dx.doi.org/10.1016/j.apsb.2023.08.008 |