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Preserving genome integrity: The vital role of SUMO-targeted ubiquitin ligases

Various post-translational modifications (PTMs) collaboratively fine-tune protein activities. SUMO-targeted ubiquitin E3 ligases (STUbLs) emerge as specialized enzymes that recognize SUMO-modified substrates through SUMO-interaction motifs and subsequently ubiquitinate them via the RING domain, ther...

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Detalles Bibliográficos
Autores principales: Han, Jinhua, Mu, Yanhua, Huang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692494/
https://www.ncbi.nlm.nih.gov/pubmed/38047137
http://dx.doi.org/10.1016/j.cellin.2023.100128