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Preserving genome integrity: The vital role of SUMO-targeted ubiquitin ligases
Various post-translational modifications (PTMs) collaboratively fine-tune protein activities. SUMO-targeted ubiquitin E3 ligases (STUbLs) emerge as specialized enzymes that recognize SUMO-modified substrates through SUMO-interaction motifs and subsequently ubiquitinate them via the RING domain, ther...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692494/ https://www.ncbi.nlm.nih.gov/pubmed/38047137 http://dx.doi.org/10.1016/j.cellin.2023.100128 |