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Cytokine and lipid metabolome effects of low-dose acetylsalicylic acid in critically ill patients with systemic inflammation: a pilot, feasibility, multicentre, randomised, placebo-controlled trial

Objective: The systemic inflammatory response syndrome (SIRS) is a dysregulated response that contributes to critical illness. Adjunctive acetylsalicylic acid (ASA) treatment may offer beneficial effects by increasing the synthesis of specialised proresolving mediators (a subset of polyunsaturated f...

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Detalles Bibliográficos
Autores principales: Cioccari, Luca, Luethi, Nora, Duong, Thy, Ryan, Eileen, Cutuli, Salvatore L., Lloyd-Donald, Patryck, Eastwood, Glenn M., Peck, Leah, Young, Helen, Vaara, Suvi T., French, Craig J., Orford, Neil, Dwivedi, Jyotsna, Lankadeva, Yugeesh R., Bailey, Michael, Reid, Gavin E., Bellomo, Rinaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692583/
https://www.ncbi.nlm.nih.gov/pubmed/32900329
http://dx.doi.org/10.1016/S1441-2772(23)00390-3