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Lupeol synergizes with 5-fluorouracil to combat c-MET/EphA2 mediated chemoresistance in triple negative breast cancer

Triple-negative breast cancer (TNBC) is the most elusive subtype of breast cancer that encounters treatment dilemmas owing to the paucity of druggable targets. We found hyperactivation of c-MET and ephrin type-A receptor 2 (EphA2) in patients treated with 5FU driven chemotherapy which correlated wit...

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Detalles Bibliográficos
Autores principales: Mitra, Debarpan, Saha, Depanwita, Das, Gaurav, Mukherjee, Rimi, Banerjee, Samir, Alam, Neyaz, Mustafi, Saunak Mitra, Nath, Partha, Majumder, Anuj, Majumder, Biswanath, Murmu, Nabendu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692664/
https://www.ncbi.nlm.nih.gov/pubmed/38047085
http://dx.doi.org/10.1016/j.isci.2023.108395