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Tissue factor targeting peptide enhances nanoparticle binding and delivery of a synthetic specialized pro-resolving lipid mediator to injured arteries
BACKGROUND: Specialized pro-resolving lipid mediators (SPM) such as resolvin D1 (RvD1) attenuate inflammation and exhibit vasculo-protective properties. METHODS: We investigated poly-lactic-co-glycolic acid (PLGA)-based nanoparticles (NP), containing a peptide targeted to tissue factor (TF) for deli...
Autores principales: | Levy, Elizabeth S., Kim, Alexander S., Werlin, Evan, Chen, Mian, Sansbury, Brian E., Spite, Matthew, Desai, Tejal A., Conte, Michael S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692706/ https://www.ncbi.nlm.nih.gov/pubmed/38045567 http://dx.doi.org/10.1016/j.jvssci.2023.100126 |
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