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Peptides designed from a bacteriophage capsid protein function as synthetic transcription repressors

The bacteriophage capsid protein, Psu (polarity suppression), inhibits the bacterial transcription terminator, Rho. In an effort to find nontraditional antibacterial agents, we previously designed peptides from the Psu C terminus that function as inhibitors of Rho. Here, we demonstrated that these p...

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Detalles Bibliográficos
Autores principales: Sharma, Pankaj V., Jain, Sriyans, Sen, Ranjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692717/
https://www.ncbi.nlm.nih.gov/pubmed/37865318
http://dx.doi.org/10.1016/j.jbc.2023.105373