Mitochondrial hydrogen peroxide production by pyruvate dehydrogenase and α-ketoglutarate dehydrogenase in oxidative eustress and oxidative distress

Pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase (KGDH) are vital entry points for monosaccharides and amino acids into the Krebs cycle and thus integral for mitochondrial bioenergetics. Both complexes produce mitochondrial hydrogen peroxide (mH(2)O(2)) and are deactivated by electroph...

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Detalles Bibliográficos
Autores principales: Chalifoux, Olivia, Faerman, Ben, Mailloux, Ryan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
JBC Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692731/
https://www.ncbi.nlm.nih.gov/pubmed/37898400
http://dx.doi.org/10.1016/j.jbc.2023.105399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692731/
https://www.ncbi.nlm.nih.gov/pubmed/37898400
http://dx.doi.org/10.1016/j.jbc.2023.105399

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