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Cyclase-associated protein interacts with actin filament barbed ends to promote depolymerization and formin displacement

Cyclase-associated protein (CAP) has emerged as a central player in cellular actin turnover, but its molecular mechanisms of action are not yet fully understood. Recent studies revealed that the N terminus of CAP interacts with the pointed ends of actin filaments to accelerate depolymerization in co...

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Detalles Bibliográficos
Autores principales: Alimov, Nikita, Hoeprich, Gregory J., Padrick, Shae B., Goode, Bruce L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692737/
https://www.ncbi.nlm.nih.gov/pubmed/37863260
http://dx.doi.org/10.1016/j.jbc.2023.105367