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Targeting SIRT1 synergistically improves the antitumor effect of JQ-1 in hepatocellular carcinoma
Bromodomain and extraterminal domain protein inhibitors have shown therapeutic promise in hepatocellular carcinoma. However, resistance to bromodomain and extraterminal domain protein inhibitors has emerged in preclinical trials, presenting an immense clinical challenge, and the mechanisms are uncle...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692793/ https://www.ncbi.nlm.nih.gov/pubmed/38045194 http://dx.doi.org/10.1016/j.heliyon.2023.e22093 |