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cellsig plug-in enhances CIBERSORTx signature selection for multidataset transcriptomes with sparse multilevel modelling

MOTIVATION: The precise characterization of cell-type transcriptomes is pivotal to understanding cellular lineages, deconvolution of bulk transcriptomes, and clinical applications. Single-cell RNA sequencing resources like the Human Cell Atlas have revolutionised cell-type profiling. However, challe...

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Detalles Bibliográficos
Autores principales: Al Kamran Khan, Md Abdullah, Wu, Jian, Sun, Yuhan, Barrow, Alexander D, Papenfuss, Anthony T, Mangiola, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692870/
https://www.ncbi.nlm.nih.gov/pubmed/37952182
http://dx.doi.org/10.1093/bioinformatics/btad685