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Improving DNA vaccination performance through a new microbubble design and an optimized sonoporation protocol
As a non-viral transfection method, ultrasound and microbubble-induced sonoporation can achieve spatially targeted gene delivery with synergistic immunostimulatory effects. Here, we report for the first time the application of sonoporation for improving DNA vaccination performance. This study develo...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692915/ https://www.ncbi.nlm.nih.gov/pubmed/37976565 http://dx.doi.org/10.1016/j.ultsonch.2023.106685 |