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Improving DNA vaccination performance through a new microbubble design and an optimized sonoporation protocol

As a non-viral transfection method, ultrasound and microbubble-induced sonoporation can achieve spatially targeted gene delivery with synergistic immunostimulatory effects. Here, we report for the first time the application of sonoporation for improving DNA vaccination performance. This study develo...

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Detalles Bibliográficos
Autores principales: Shi, Yuanchao, Weng, Weixiong, Chen, Mengting, Huang, Haoqiang, Chen, Xin, Peng, Yin, Hu, Yaxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692915/
https://www.ncbi.nlm.nih.gov/pubmed/37976565
http://dx.doi.org/10.1016/j.ultsonch.2023.106685