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Protein arginine N-methyltransferase 2 plays a noncatalytic role in the histone methylation activity of PRMT1

Protein arginine N-methyltransferases are a family of epigenetic enzymes responsible for monomethylation or dimethylation of arginine residues on histones. Dysregulation of protein arginine N-methyltransferase activity can lead to aberrant gene expression and cancer. Recent studies have shown that P...

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Detalles Bibliográficos
Autores principales: Rowley, Michael J., Prout-Holm, Riley A., Liu, Rui Wen, Hendrickson-Rebizant, Thordur, Ige, Olufola O., Lakowski, Ted M., Frankel, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692916/
https://www.ncbi.nlm.nih.gov/pubmed/37863263
http://dx.doi.org/10.1016/j.jbc.2023.105360