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MIOX inhibits autophagy to regulate the ROS -driven inhibition of STAT3/c-Myc-mediated epithelial-mesenchymal transition in clear cell renal cell carcinoma

The specific mechanism of clear cell renal cell carcinoma (ccRCC) progression, a pathological type that accounts for the highest proportion of RCC, remains unclear. In this study, bioinformatics analysis of scRNA-seq dataset in ccRCC revealed that MIOX was a gene specifically down-regulated in tumor...

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Detalles Bibliográficos
Autores principales: Meng, Longxiyu, Gao, Jie, Mo, Wenjing, Wang, Baojun, Shen, Hongwei, Cao, Wenmin, Ding, Meng, Diao, Wenli, Chen, Wei, Zhang, Qing, Shu, Jiaxin, Dai, Huiqi, Guo, Hongqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692917/
https://www.ncbi.nlm.nih.gov/pubmed/37977044
http://dx.doi.org/10.1016/j.redox.2023.102956