A novel CPT1A covalent inhibitor modulates fatty acid oxidation and CPT1A-VDAC1 axis with therapeutic potential for colorectal cancer

Colorectal cancer (CRC) is a common and deadly disease of the digestive system, but its targeted therapy is hampered by the lack of reliable and specific biomarkers. Hence, discovering new therapeutic targets and agents for CRC is an urgent and challenging task. Here we report that carnitine palmito...

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Detalles Bibliográficos
Autores principales: Hu, Anni, Wang, Hang, Xu, Qianqian, Pan, Yuqi, Jiang, Zeyu, Li, Sheng, Qu, Yi, Hu, Yili, Wu, Hao, Wang, Xinzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692921/
https://www.ncbi.nlm.nih.gov/pubmed/37977042
http://dx.doi.org/10.1016/j.redox.2023.102959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692921/
https://www.ncbi.nlm.nih.gov/pubmed/37977042
http://dx.doi.org/10.1016/j.redox.2023.102959

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