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Differential interactome mapping of aggregation prone/prion-like proteins under stress: novel links to stress granule biology

BACKGROUND: Aberrant stress granules (SGs) are emerging as prime suspects in the nucleation of toxic protein aggregates. Understanding the molecular networks linked with aggregation-prone proteins (prion protein, synuclein, and tau) under stressful environments is crucial to understand pathophysiolo...

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Detalles Bibliográficos
Autores principales: Younas, Neelam, Zafar, Saima, Saleem, Tayyaba, Fernandez Flores, Leticia Camila, Younas, Abrar, Schmitz, Matthias, Zerr, Inga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693047/
https://www.ncbi.nlm.nih.gov/pubmed/38041189
http://dx.doi.org/10.1186/s13578-023-01164-7