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Alterations in the mammary gland and tumor microenvironment of formerly obese mice

BACKGROUND: Obesity is a risk factor for breast cancer, and women with obesity that develop breast cancer have a worsened prognosis. Within the mammary gland, obesity causes chronic, macrophage-driven inflammation and adipose tissue fibrosis. Weight loss is a recommended intervention to resolve obes...

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Detalles Bibliográficos
Autores principales: Kuziel, Genevra, Moore, Brittney N., Haugstad, Grace P., Xiong, Yue, Williams, Abbey E., Arendt, Lisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693119/
https://www.ncbi.nlm.nih.gov/pubmed/38041006
http://dx.doi.org/10.1186/s12885-023-11688-3