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MLKL deficiency alleviates neuroinflammation and motor deficits in the α-synuclein transgenic mouse model of Parkinson’s disease

Parkinson’s disease (PD), one of the most devastating neurodegenerative brain disorders, is characterized by the progressive loss of dopaminergic neurons in the substantia nigra (SN) and deposits of α-synuclein aggregates. Currently, pharmacological interventions for PD remain inadequate. The cell n...

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Detalles Bibliográficos
Autores principales: Geng, Lu, Gao, Wenqing, Saiyin, Hexige, Li, Yuanyuan, Zeng, Yu, Zhang, Zhifei, Li, Xue, Liu, Zuolong, Gao, Qiang, An, Ping, Jiang, Ning, Yu, Xiaofei, Chen, Xiangjun, Li, Suhua, Chen, Lei, Lu, Boxun, Li, Aiqun, Chen, Guoyuan, Shen, Yidong, Zhang, Haibing, Tian, Mei, Zhang, Zhuohua, Li, Jixi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693130/
https://www.ncbi.nlm.nih.gov/pubmed/38041169
http://dx.doi.org/10.1186/s13024-023-00686-5