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Targeting MHC-I molecules for cancer: function, mechanism, and therapeutic prospects

The molecules of Major histocompatibility class I (MHC-I) load peptides and present them on the cell surface, which provided the immune system with the signal to detect and eliminate the infected or cancerous cells. In the context of cancer, owing to the crucial immune-regulatory roles played by MHC...

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Detalles Bibliográficos
Autores principales: Wu, Xiangyu, Li, Tianhang, Jiang, Rui, Yang, Xin, Guo, Hongqian, Yang, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693139/
https://www.ncbi.nlm.nih.gov/pubmed/38041084
http://dx.doi.org/10.1186/s12943-023-01899-4