Cargando…
Targeting MHC-I molecules for cancer: function, mechanism, and therapeutic prospects
The molecules of Major histocompatibility class I (MHC-I) load peptides and present them on the cell surface, which provided the immune system with the signal to detect and eliminate the infected or cancerous cells. In the context of cancer, owing to the crucial immune-regulatory roles played by MHC...
Autores principales: | Wu, Xiangyu, Li, Tianhang, Jiang, Rui, Yang, Xin, Guo, Hongqian, Yang, Rong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693139/ https://www.ncbi.nlm.nih.gov/pubmed/38041084 http://dx.doi.org/10.1186/s12943-023-01899-4 |
Ejemplares similares
-
Targeting MDSC for Immune-Checkpoint Blockade in Cancer Immunotherapy: Current Progress and New Prospects
por: Li, Tianhang, et al.
Publicado: (2021) -
Commentary: High-metastatic melanoma cells promote the metastatic capability of low-metastatic melanoma cells via exosomal transfer of miR-411-5p
por: Li, Tianhang, et al.
Publicado: (2022) -
Selector function of MHC I molecules is determined by protein plasticity
por: Bailey, Alistair, et al.
Publicado: (2015) -
Chaperone function in antigen presentation by MHC class I molecules—tapasin in the PLC and TAPBPR beyond
por: Margulies, David H., et al.
Publicado: (2023) -
Non-classical MHC Class I molecules regulating natural killer cell function
por: Smyth, Mark J., et al.
Publicado: (2013)