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Predicting drug response from single-cell expression profiles of tumours

BACKGROUND: Intra-tumour heterogeneity (ITH) presents a significant obstacle in formulating effective treatment strategies in clinical practice. Single-cell RNA sequencing (scRNA-seq) has evolved as a powerful instrument for probing ITH at the transcriptional level, offering an unparalleled opportun...

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Detalles Bibliográficos
Autores principales: Pellecchia, Simona, Viscido, Gaetano, Franchini, Melania, Gambardella, Gennaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693176/
https://www.ncbi.nlm.nih.gov/pubmed/38041118
http://dx.doi.org/10.1186/s12916-023-03182-1