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Baffled‐flow culture system enables the mass production of megakaryocytes from human embryonic stem cells by enhancing mitochondrial function

Human embryonic stem cells (hESCs) have become an ideal cell source for the ex vivo generation of megakaryocyte (MK) and platelet products for clinical applications. However, an ongoing challenge is to establish scalable culture systems to maximize the yield of stem cell‐derived MKs that release pla...

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Detalles Bibliográficos
Autores principales: Wu, Xumin, Zhang, Bowen, Chen, Keyi, Zhao, Jiahui, Li, Yunxing, Li, Jisheng, Liu, Chuanli, He, Lijuan, Fan, Tao, Wang, Chao, Li, Yan, Pei, Xuetao, Li, Yanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693187/
https://www.ncbi.nlm.nih.gov/pubmed/37088551
http://dx.doi.org/10.1111/cpr.13484