Computer-Assisted Drug Discovery of a Novel Theobromine Derivative as an EGFR Protein-Targeted Apoptosis Inducer

The overexpression of the Epidermal Growth Factor Receptor (EGFR) marks it as a pivotal target in cancer treatment, with the aim of reducing its proliferation and inducing apoptosis. This study aimed at the CADD of a new apoptotic EGFR inhibitor. The natural alkaloid, theobromine, was used as a star...

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Detalles Bibliográficos
Autores principales: Eissa, Ibrahim H, Yousef, Reda G, Elkaeed, Eslam B, Alsfouk, Aisha A, Husein, Dalal Z, Ibrahim, Ibrahim M, El-Mahdy, Hesham A, Elkady, Hazem, Metwaly, Ahmed M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693208/
https://www.ncbi.nlm.nih.gov/pubmed/38046652
http://dx.doi.org/10.1177/11769343231217916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693208/
https://www.ncbi.nlm.nih.gov/pubmed/38046652
http://dx.doi.org/10.1177/11769343231217916

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