Niraparib restrains prostate cancer cell proliferation and metastasis and tumor growth in mice by regulating the lncRNA MEG3/miR-181-5p/GATA6 pathway

BACKGROUND: Poly (ADP-ribose) polymerase (PARP) inhibitors (PARPi), have gained approval for treating patients with castration-resistant prostate cancer (CRPC). Maternally expressed gene 3 (MEG3), a long non-coding RNA (lncRNA), plays a role in inhibiting tumorigenesis through regulating DNA repair...

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Detalles Bibliográficos
Autores principales: Cheng, Ji, Sun, Yi, Zhao, Huacai, Ren, Wei, Gao, Dan, Wang, Zhigang, Lv, Wei, Dong, Qingchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693232/
https://www.ncbi.nlm.nih.gov/pubmed/38047026
http://dx.doi.org/10.7717/peerj.16314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693232/
https://www.ncbi.nlm.nih.gov/pubmed/38047026
http://dx.doi.org/10.7717/peerj.16314

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