Blockage of EGFR/AKT and mevalonate pathways synergize the antitumor effect of temozolomide by reprogramming energy metabolism in glioblastoma

BACKGROUND: Metabolism reprogramming plays a vital role in glioblastoma (GBM) progression and recurrence by producing enough energy for highly proliferating tumor cells. In addition, metabolic reprogramming is crucial for tumor growth and immune‐escape mechanisms. Epidermal growth factor receptor (E...

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Detalles Bibliográficos
Autores principales: Cui, Xiaoteng, Zhao, Jixing, Li, Guanzhang, Yang, Chao, Yang, Shixue, Zhan, Qi, Zhou, Junhu, Wang, Yunfei, Xiao, Menglin, Hong, Biao, Yi, Kaikai, Tong, Fei, Tan, Yanli, Wang, Hu, Wang, Qixue, Jiang, Tao, Fang, Chuan, Kang, Chunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693308/
https://www.ncbi.nlm.nih.gov/pubmed/37920878
http://dx.doi.org/10.1002/cac2.12502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693308/
https://www.ncbi.nlm.nih.gov/pubmed/37920878
http://dx.doi.org/10.1002/cac2.12502

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