Structural basis for T cell recognition of cancer neoantigens and implications for predicting neoepitope immunogenicity

Adoptive cell therapy (ACT) with tumor-specific T cells has been shown to mediate durable cancer regression. Tumor-specific T cells are also the basis of other therapies, notably cancer vaccines. The main target of tumor-specific T cells are neoantigens resulting from mutations in self-antigens over...

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Detalles Bibliográficos
Autores principales: Mariuzza, Roy A., Wu, Daichao, Pierce, Brian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693334/
https://www.ncbi.nlm.nih.gov/pubmed/38045695
http://dx.doi.org/10.3389/fimmu.2023.1303304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693334/
https://www.ncbi.nlm.nih.gov/pubmed/38045695
http://dx.doi.org/10.3389/fimmu.2023.1303304

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