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Structural basis for T cell recognition of cancer neoantigens and implications for predicting neoepitope immunogenicity
Adoptive cell therapy (ACT) with tumor-specific T cells has been shown to mediate durable cancer regression. Tumor-specific T cells are also the basis of other therapies, notably cancer vaccines. The main target of tumor-specific T cells are neoantigens resulting from mutations in self-antigens over...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693334/ https://www.ncbi.nlm.nih.gov/pubmed/38045695 http://dx.doi.org/10.3389/fimmu.2023.1303304 |