GABA(A) receptor-mediated seizure liabilities: a mixed-methods screening approach

GABA(A) receptors, members of the pentameric ligand-gated ion channel superfamily, are widely expressed in the central nervous system and mediate a broad range of pharmaco-toxicological effects including bidirectional changes to seizure threshold. Thus, detection of GABA(A) receptor-mediated seizure...

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Detalles Bibliográficos
Autores principales: Bampali, Konstantina, Koniuszewski, Filip, Vogel, Florian D., Fabjan, Jure, Andronis, Christos, Lekka, Eftychia, Virvillis, Vassilis, Seidel, Thomas, Delaunois, Annie, Royer, Leandro, Rolf, Michael G., Giuliano, Chiara, Traebert, Martin, Roussignol, Gautier, Fric-Bordat, Magali, Mazelin-Winum, Ludmilla, Bryant, Sharon D., Langer, Thierry, Ernst, Margot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693519/
https://www.ncbi.nlm.nih.gov/pubmed/37093397
http://dx.doi.org/10.1007/s10565-023-09803-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693519/
https://www.ncbi.nlm.nih.gov/pubmed/37093397
http://dx.doi.org/10.1007/s10565-023-09803-y

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