Assay conditions for estimating differences in base excision repair activity with Fpg-modified comet assay

DNA repair is an essential agent in cancer development, progression, prognosis, and response to therapy. We have adapted a cellular repair assay based on the formamidopyrimidine DNA glycosylase (Fpg)-modified comet assay to assess DNA repair kinetics. The removal of oxidized nucleobases over time (0...

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Detalles Bibliográficos
Autores principales: Zheng, Congying, Collins, Andrew, Brunborg, Gunnar, van Schooten, Frederik-Jan, Nordengen, Anne Lene, Shaposhnikov, Sergey, Godschalk, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693524/
https://www.ncbi.nlm.nih.gov/pubmed/36932276
http://dx.doi.org/10.1007/s10565-023-09801-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693524/
https://www.ncbi.nlm.nih.gov/pubmed/36932276
http://dx.doi.org/10.1007/s10565-023-09801-0

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