A high-throughput metabolomics in vitro platform for the characterization of hepatotoxicity

Cell-based metabolomics provides multiparametric physiologically relevant readouts that can be highly advantageous for improved, biologically based decision making in early stages of compound development. Here, we present the development of a 96-well plate LC-MS/MS-based targeted metabolomics screen...

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Detalles Bibliográficos
Autores principales: Ramirez-Hincapie, Sabina, Birk, Barbara, Ternes, Philipp, Giri, Varun, Haake, Volker, Herold, Michael, Zickgraf, Franziska Maria, Verlohner, Andreas, Huener, Hans-Albrecht, Kamp, Hennicke, Driemert, Peter, Landsiedel, Robert, Richling, Elke, Funk-Weyer, Dorothee, van Ravenzwaay, Bennard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693528/
https://www.ncbi.nlm.nih.gov/pubmed/37138123
http://dx.doi.org/10.1007/s10565-023-09809-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693528/
https://www.ncbi.nlm.nih.gov/pubmed/37138123
http://dx.doi.org/10.1007/s10565-023-09809-6

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