Programmable de novo designed coiled coil-mediated phase separation in mammalian cells

Membraneless liquid compartments based on phase-separating biopolymers have been observed in diverse cell types and attributed to weak multivalent interactions predominantly based on intrinsically disordered domains. The design of liquid-liquid phase separated (LLPS) condensates based on de novo des...

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Detalles Bibliográficos
Autores principales: Ramšak, Maruša, Ramirez, Dominique A., Hough, Loren E., Shirts, Michael R., Vidmar, Sara, Eleršič Filipič, Kristina, Anderluh, Gregor, Jerala, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693550/
https://www.ncbi.nlm.nih.gov/pubmed/38042897
http://dx.doi.org/10.1038/s41467-023-43742-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693550/
https://www.ncbi.nlm.nih.gov/pubmed/38042897
http://dx.doi.org/10.1038/s41467-023-43742-w

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