Mechanistic manifold in a hemoprotein-catalyzed cyclopropanation reaction with diazoketone

Hemoproteins have recently emerged as promising biocatalysts for new-to-nature carbene transfer reactions. However, mechanistic understanding of the interplay between productive and unproductive pathways in these processes is limited. Using spectroscopic, structural, and computational methods, we in...

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Detalles Bibliográficos
Autores principales: Nam, Donggeon, Bacik, John-Paul, Khade, Rahul L., Aguilera, Maria Camila, Wei, Yang, Villada, Juan D., Neidig, Michael L., Zhang, Yong, Ando, Nozomi, Fasan, Rudi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693563/
https://www.ncbi.nlm.nih.gov/pubmed/38042860
http://dx.doi.org/10.1038/s41467-023-43559-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693563/
https://www.ncbi.nlm.nih.gov/pubmed/38042860
http://dx.doi.org/10.1038/s41467-023-43559-7

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