IGF2 prevents dopaminergic neuronal loss and decreases intracellular alpha-synuclein accumulation in Parkinson’s disease models

Parkinson’s disease (PD) is the second most common late-onset neurodegenerative disease and the predominant cause of movement problems. PD is characterized by motor control impairment by extensive loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc). This selective dopaminergic...

Descripción completa

Detalles Bibliográficos
Autores principales: Arcos, Javiera, Grunenwald, Felipe, Sepulveda, Denisse, Jerez, Carolina, Urbina, Valentina, Huerta, Tomas, Troncoso-Escudero, Paulina, Tirado, Daniel, Perez, Angela, Diaz-Espinoza, Rodrigo, Nova, Esteban, Kubitscheck, Ulrich, Rodriguez-Gatica, Juan Eduardo, Hetz, Claudio, Toledo, Jorge, Ahumada, Pablo, Rojas-Rivera, Diego, Martín-Montañez, Elisa, Garcia-Fernandez, María, Vidal, René L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693583/
https://www.ncbi.nlm.nih.gov/pubmed/38042807
http://dx.doi.org/10.1038/s41420-023-01734-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693583/
https://www.ncbi.nlm.nih.gov/pubmed/38042807
http://dx.doi.org/10.1038/s41420-023-01734-1

Ejemplares similares