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Amlodipine and lufenuron as repurposing drugs against Sporothrix brasiliensis

BACKGROUND: Sporotrichosis caused by Sporothrix brasiliensis is a globally emerging infectious disease with limited therapeutic options. Thus, we aimed to evaluate the in vitro activity of amlodipine (AML) and lufenuron (LUF) alone and their interaction with itraconazole (ITZ), the first-choice drug...

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Detalles Bibliográficos
Autores principales: Poester, Vanice Rodrigues, Hidalgo, Jéssica Estefania Dávila, Jardim, Lara Severo, Trápaga, Mariana Rodrigues, Rabello, Vanessa Brito de Souza, Almeida-Paes, Rodrigo, Zancope-Oliveira, Rosely Maria, Xavier, Melissa Orzechowski
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693817/
https://www.ncbi.nlm.nih.gov/pubmed/38050607
http://dx.doi.org/10.7717/peerj.16443