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Mechanisms of myeloid leukemogenesis: Current perspectives and therapeutic objectives

Acute myeloid leukemia (AML) is a heterogeneous hematopoietic neoplasm which results in clonal proliferation of abnormally differentiated hematopoietic cells. In this review, mechanisms contributing to myeloid leukemogenesis are summarized, highlighting aberrations of epigenetics, transcription fact...

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Detalles Bibliográficos
Autores principales: Bouligny, Ian M., Maher, Keri R., Grant, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693933/
https://www.ncbi.nlm.nih.gov/pubmed/35989139
http://dx.doi.org/10.1016/j.blre.2022.100996