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Mechanisms of myeloid leukemogenesis: Current perspectives and therapeutic objectives
Acute myeloid leukemia (AML) is a heterogeneous hematopoietic neoplasm which results in clonal proliferation of abnormally differentiated hematopoietic cells. In this review, mechanisms contributing to myeloid leukemogenesis are summarized, highlighting aberrations of epigenetics, transcription fact...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693933/ https://www.ncbi.nlm.nih.gov/pubmed/35989139 http://dx.doi.org/10.1016/j.blre.2022.100996 |