Spreading of Tau Protein Does Not Depend on Aggregation Propensity

The stereotypical progression of Tau pathology during Alzheimer disease has been attributed to trans-neuronal spreading of misfolded Tau proteins, followed by prion-like templated aggregation of Tau. The nature of Tau and the cellular mechanisms of Tau spreading are still under debate. We hypothesiz...

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Detalles Bibliográficos
Autores principales: Rodrigues, Sara, Anglada-Huguet, Marta, Hochgräfe, Katja, Kaniyappan, Senthilvelrajan, Wegmann, Susanne, Mandelkow, Eva-Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694122/
https://www.ncbi.nlm.nih.gov/pubmed/37606769
http://dx.doi.org/10.1007/s12031-023-02143-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694122/
https://www.ncbi.nlm.nih.gov/pubmed/37606769
http://dx.doi.org/10.1007/s12031-023-02143-w

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