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SOX2 promotes vasculogenic mimicry by accelerating glycolysis via the lncRNA AC005392.2-GLUT1 axis in colorectal cancer

Vasculogenic mimicry (VM), a new model of angiogenesis, fulfills the metabolic demands of solid tumors and contributes to tumor aggressiveness. Our previous study demonstrated the effect of SOX2 in promoting VM in colorectal cancer (CRC). However, the underlying mechanisms behind this effect remain...

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Detalles Bibliográficos
Autores principales: Huang, Shimiao, Wang, Xuan, Zhu, Yin, Wang, Yadong, Chen, Jiaxuan, Zheng, Haoxuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694132/
https://www.ncbi.nlm.nih.gov/pubmed/38044399
http://dx.doi.org/10.1038/s41419-023-06274-1