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Total Astragalus saponins can reverse type 2 diabetes mellitus-related intestinal dysbiosis and hepatic insulin resistance in vivo

OBJECTIVE: Intestinal flora homeostasis in rats with type 2 diabetes mellitus (T2DM) was evaluated to explore the effects of total Astragalus saponins (TAS) on hepatic insulin resistance (IR). METHODS: Six-week-old male Sprague–Dawley rats were fed high-fat and high-sugar diet for 4 weeks and intrap...

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Detalles Bibliográficos
Autores principales: Ma, Leilei, La, Xiaojin, Zhang, Biwei, Xu, Wenxuan, Tian, Chunyu, Fu, Qianru, Wang, Meng, Wu, Chenxi, Chen, Zhen, Chang, Hong, Li, Ji-an
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694298/
http://dx.doi.org/10.3389/fendo.2023.1190827