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Differential expression of HIF1A and its downstream target VEGFA in the main subtypes of renal cell carcinoma and their impact on patient survival

Renal cell carcinoma (RCC) represents around 3% of all cancers, with the most frequent histological types being clear-cell RCC (ccRCC), followed by papillary (pRCC) and chromophobe (chRCC). Hypoxia-inducible factors (HIFs), which promote the expression of various target genes, including vascular end...

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Detalles Bibliográficos
Autores principales: Strikic, Ante, Kokeza, Josipa, Ogorevc, Marin, Kelam, Nela, Vukoja, Martina, Dolonga, Petar, Tomas, Sandra Zekic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694430/
http://dx.doi.org/10.3389/fonc.2023.1287239